Some Aspects of Pituitary-Adrenal and Autonomic Nervous Systems Functioning in Patients with Chronic Consciousness Disorders

Patients with chronic disorders of consciousness (CDoC) have various variants the pathological organization functions including sympathetic hyperactivity and hormonal changes. The objective: to determine severity paroxysmal (PSH), function pituitary-adrenal system in patients CDoC. Subjects Methods. 54 CDoC were enrolled study. randomized groups depending on assessment Coma Recovery Scale-Revised scale CRS-R index calculation. PSH was assessed 7 times a day for two days. During first week from moment admission, blood sampling performed study levels ACTH cortisol. Results. syndrome detected all groups, there no significant dependencies its time day. There differences cortisol during Conclusions: is observed most In CDoC, daily rhythm secretion are disrupted.